VITAMIN-C
Based on scientific evidences Vitamin C contributes to:
- the protection of cells from oxidative stress
- to normal collagen formation for the normal function of cartilage
- to normal collagen formation for the normal function of bones
- to the normal function of the immune system
Initial studies identi ed vitamin C as a critical modulator of the production of collagen, and has potent antioxidantt effects. Several in vitro studies have shown that vitamin C plays an important role in promoting expression of genes involved in differentiation of chondrocytes1,2 Vitamin C possessed multiple capacities for prevention of OA progress, including a decrease in apoptosis and in the expression of pro- in ammatory cytokines and MMPs in addition to the well-known antioxidation.2
Patrick Aghajanian et al, The Roles and Mechanisms of Actions of Vitamin C in Bone: New Developments, Journal of Bone and Mineral Research, Vol. 30, No. 11, November 2015, pp 1945–195Chiu PR et al, Vitamin C Protects .02 Chondrocytes against Monosodium Iodoacetate-Induced Osteoarthritis by Multiple Pathways. Int J Mol Sci. 2016
Dec 27;18(1). pii: E38. doi: 10.3390/ .ijms18010038
